epidemiology of methicillin-resistant staphylococcus aureus isolated from health care providers in mofid children hospital

نویسندگان

masoumeh navidinia department of laboratory sciences, faculty of paramedical sciences, shahid beheshti university of medical sciences, tehran, ir iran; department of laboratory sciences, faculty of paramedical sciences, shahid beheshti university of medical sciences, tehran, ir iran. tel: +98-2126850560سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences)

fatemeh fallah pediatric infections research center, mofid children’s hospital, shahid beheshti university of medical sciences, tehran, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences)

behnaz lajevardi pediatric infections research center, mofid children’s hospital, shahid beheshti university of medical sciences, tehran, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences)

mehdi shirdoost pediatric infections research center, mofid children’s hospital, shahid beheshti university of medical sciences, tehran, ir iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (shahid beheshti university of medical sciences)

چکیده

conclusions carrier samples screening is considered inferior to clinical samples. treatment of a variety of infectious diseases is difficult due to resistant bacteria. consequently, annual screening of these individuals, detecting the carriers and decolonizing them to reduce transmission of s. aureus in the hospital are necessary. background methicillin-resistant staphylococcus aureus (mrsa) is one of the most important agents producing nosocomial diseases in hospitalized children. consequently, screening of in hospital health care providers who are in direct contact with patients is necessary. objectives the aim of this study was to determine the prevalence of mrsa in health care providers, their antimicrobial resistance pattern and staphylococcal cassette chromosome mec (sccmec) typing. materials and methods two hundred and twenty nine health care providers were examined and nasal samples were sent for s. aureus culture and sociodemographic data were obtained from them, during one year, from august 2012 to july 2013. after mrsa identification, all isolates were examined for antibiotic resistance pattern and sccmec typing. results staphylococci were isolated from 27 samples. twenty one of them were mrsa. the highest resistance to antibiotics was for penicillin (90.3%) and ceftazidime (77.4%). all isolates were sensitive to linezolid and vancomycin. two isolates (9%) had sccmec i, five (23%) had sccmec ii, nine (42%) had sccmec iii, and one (4%) had sccmec iv. four isolates were nontypable by using the published primers, perhaps indicating the existence of a novel sccmec class.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

prophage typing of methicillin resistant staphylococcus aureus isolated from a tertiary care hospital in tehran, iran

background staphylococcus aureus is a common cause of infections among humans and animals and it is known as a community-acquired and nosocomial pathogen. most of the isolates contain lysogenic phages which are responsible for production of various virulence factors such as enterotoxins, staphylokinase, β-lysin, lipase, exfoliative toxin a and pantone-vlaentine leukociden (pvl). all staphylococ...

متن کامل

detection of inducible clindamycin resistance (mlsbi) among methicillin-resistant staphylococcus aureus (mrsa) isolated from health care providers

methicillin-resistant staphylococcus aureus (mrsa) is one of the most important agents producing nosocomial diseases in hospitalized children. then, screening of health care providers who are in direct contact with patients in hospital is necessary. the objective of this study was to investigate mrsa collected isolates for mlsb phenotypes, in particular inducible clindamycin resistance (mlsbi)....

متن کامل

Nasal Colonization Rate of Community and Hospital Acquired Methicillin Resistant Staphylococcus Aureus in Hospitalized Children

Background & Aims: Prevalence of community and hospital acquired methicillin-resistant Staphylococcus aureus (MRSA) infection is increasing. The primary reservoir is the anterior nares; and nasal carriage is a risk factor for infection in a variety of populations. Infection due to hospital-acquired colonization is different from community acquired in clinical manifestations and antibiotics susc...

متن کامل

Methicillin Resistant Profile of Staphylococcus aureus Isolated from Apparently Healthy Students in Edo State University Uzairue

 Background and purpose: Staphylococcus aureus is a bacterium that causes disease in humans due to its pathogenic nature and is more responsible for infections than other Staphylococcus species. Methicillin-resistance Staphylococcus aureus (MRSA) is resistant to antibiotics and such as penicillins, cephalosporins and their derivatives has β-lactam rings. This study aimed to isolate and investig...

متن کامل

Phenotypic and Genotypic Evaluation of Methicillin-resistant Staphylococcus aureus Strains Isolated from Children in Tehran Children's Medical Center, 2016

Background and purpose: The aims of this study were to evaluate the antibiotic resistance of Healthcare-associated Methicillin-resistant Staphylococcus aureus (HA-MRSA) and Community associated MRSA (CA-MRSA)-resistant strains of Staphylococcus aureus strains and to investigate the frequency of different types of spa typing, SCCmec I, II, III, IV, V, and type IV, among the strains of MRSA isol...

متن کامل

Molecular epidemiology of methicillin-resistant Staphylococcus aureus.

Subtyping methicillin- resistant Staphylococcus aureus (MRSA) isolates and tracking nosocomial infections have evolved from phenotypic to genotypic approaches; most laboratories now depend on pulsed-field gel electrophoresis (PFGE). We discuss the limitations of current image-based genotyping methods, including PFGE, and the advantages (including ease of entering data into a database) of using ...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
archives of pediatric infectious diseases

جلد ۳، شماره ۲، صفحات ۰-۰

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023